Mechanism of Action of Natural Powerful Antioxidant - Hydroxytyrosol

In the field of natural antioxidants, hydroxytyrosol is a potent derivative of olive leaf extract, also known as 3,4-Dihydroxyphenylethanol, a light yellow viscous liquid. Hydroxytyrosol liquid for sale is well-known for its excellent properties in combating oxidative stress and inflammation and its potential in various therapeutic applications. 

Precisely because of the unique activity of hydroxytyrosol and its scarce content in plants such as olive trees, more and more people hope to obtain this active substance in a more efficient and economical way, and synthetic biology technology just meets this requirement. In this blog post, as a high quality hydroxytyrosol factory and supplier, Viablife will share with you the mechanism of action of natural powerful antioxidant - hydroxytyrosol for sale.

Better antioxidant component in olives

Hydroxytyrosol's antioxidant capacity is its most celebrated attribute. It is a phenolic compound that exhibits superior antioxidant activity compared to its counterpart, oleuropein, and even other well-known antioxidants. The ABTS+ method, a standard assay for measuring antioxidant capacity, has shown that hydroxytyrosol significantly reduces the levels of reactive oxygen species (ROS) in a concentration-dependent manner. This is crucial because ROS are known to cause cellular damage, leading to aging and various diseases.（Data Sources：Zori N , Kopjar N , Rodriguez J V ,et al. Acta Pharmaceutica, 2021(1).DOI:10.2478/ACPH-2021-0003.）

The antioxidant mechanism of hydroxytyrosol involves several pathways. It directly scavenges free radicals, thereby preventing them from oxidizing cellular components. Additionally, hydroxytyrosol has been shown to modulate the expression of genes involved in the antioxidant defense system, such as glutathione peroxidase and superoxide dismutase. This dual action makes it a formidable defender against oxidative stress.（Data Sources：D'Angelo, Stefania et al.  Free radical biology & medicine vol. 38,7 (2005): 908-19. ）

【Potential powerful anti-inflammatory components】

Inflammation is a natural response to injury and infection, but chronic inflammation can lead to numerous health issues. Hydroxytyrosol has demonstrated significant anti-inflammatory effects, particularly in skin health. Studies have shown that it can reduce the expression of pro-inflammatory cytokines such as IL-1β, IL-6, and IL-8 in human dermal fibroblasts exposed to ultraviolet (UV) radiation. This suggests that hydroxytyrosol could play a pivotal role in managing skin inflammation and promoting healing.（Data Sources：Jeon S ,  Choi M . Biomedical Dermatology, 2018, 2(1).）

【Excellent component for repairing ultraviolet damage】

The anti-inflammatory action of hydroxytyrosol is linked to its ability to inhibit the activation of nuclear factor kappa B (NF-κB), a transcription factor that controls the expression of many genes involved in inflammation. By suppressing NF-κB, hydroxytyrosol can reduce the production of inflammatory mediators, thus alleviating the inflammatory response.（Data Sources：Egeria Scoditti, Sara Carpi , Marika Massaro, et al. Nutrients 2019, 11, 2493 2 of 29）

The sun's UV rays are a significant source of oxidative stress and can lead to skin damage. Hydroxytyrosol has emerged as a potent photoprotective agent. It has been shown to protect against UVB-induced DNA damage in human skin keratinocytes by reducing ROS production and inhibiting lipid peroxidation. This protective effect is particularly important in the context of skin health, where UV exposure is a leading cause of premature aging and skin cancer.（Data Sources：Guo W , An Y , Jiang L ,et al. Phytotherapy Research, 2010, 24(3).DOI:10.1002/ptr.2943.）

The photoprotective mechanism of hydroxytyrosol is multifaceted. It can absorb UV radiation, thereby preventing it from reaching and damaging skin cells. Moreover, it can repair DNA damage caused by UV exposure and stimulate the production of enzymes that repair oxidative damage, such as catalase and glutathione S-transferase.（Data Sources：D'Angelo, Stefania et al.  Free radical biology & medicine vol. 38,7 (2005): 908-19. ）

【Potential high-efficiency antibacterial component】

Hydroxytyrosol also exhibits antibacterial properties, making it a potential candidate for use in antimicrobial  It has been found to inhibit the growth of various bacterial strains, including those resistant to common antibiotics. This is particularly significant in the era of increasing antibiotic resistance, where novel alternatives are desperately needed.（Data Sources：GIUSEPPE BISIGNANO, ANTONIO TOMAINO, ROSSELLA LO CASCIO,et al. 1999 J. Pharm. Pharmacol. ）

The antibacterial activity of hydroxytyrosol is believed to be due to its ability to disrupt bacterial cell membranes and interfere with essential cellular processes. It can also inhibit the production of virulence factors in certain bacteria, reducing their ability to cause disease.

【Brief summary】

High quality hydroxytyrosol, the powerhouse of olive leaf extract, stands as a beacon of natural health with its multifaceted benefits. From its powerful antioxidant and anti-inflammatory effects to its photoprotective and antimicrobial properties, hydroxytyrosol demonstrates the importance of natural compounds. As research continues to reveal the depth of its mechanisms, hydroxytyrosol is expected to play an important role in preventive health care. Adopting this natural antioxidant in our daily lives could be a step toward harnessing the power of nature to boost our health.

Why Choose Viablife Hydroxytyrosol for sale?

Viablife is currently the only high quality hydroxytyrosol manufacturer in China who can provide commercial scale Hydroxytyrosol using its leading Biosynthesis and Fermentation technology. Compared to plant-extracted Hydroxytyrosol, Viabife's Hydroxytyrosol has no pesticide / fertilizer residual and has very little odor, which makes it perfect for the applications in Cosmetic and Nutraceuticals & Food Additives.

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